Module

Current Data and Treatment Strategies for Controlling HIV Replication in Multiclass-Experienced Patients

Source: New Strategies for Regaining Control of HIV Replication in Treatment-Experienced Patients

Current Data and Treatment Strategies for Controlling HIV Replication in Multiclass-Experienced Patients


CME Program Director: Joseph J. Eron, Jr., MD

Faculty:

William A. O'Brien, MD, MSVictor Mulanovich, MD
  • William A. O'Brien, MD, MS
  • Victor Mulanovich, MD

CME CREDIT INFORMATION

Release Date: 03/02/06

Expiration Date: 03/01/07


Physicians: maximum of 1.75 AMA PRA Category 1 Credits™

Status: Please log in to view status

Begin the Module

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Discuss the goals of therapy in multiclass-experienced patients and strategies for optimal use of new agents to regain virologic control
  • Review recent clinical trial data on the use of approved and investigational antiretrovirals in multiclass-experienced patients
  • Discuss clinical strategies for maintaining a patient’s immunologic and clinical status while awaiting new, active agents to construct a suppressive regimen

Topics covered include:

  • Introduction
  • Goals and Strategies for Treatment-Experienced Patients
  • Initial Assessment of Treatment Failure
  • Selecting a Background Regimen in Highly Experienced Patients
  • Strategies for Using New Agents to Regain Control of HIV in Treatment-Experienced Patients
  • Enfuvirtide
  • Tipranavir
  • Investigational Second-Generation Agents: Darunavir (TMC114)
  • Investigational Second-Generation Agents: Etravirine (TMC125)
  • Investigational Second-Generation Agents: Dexelvucitabine (D-d4FC)
  • Investigational Agents in New Drug Classes: Novel Entry Inhibitors
  • Investigational Agents in New Drug Classes: Integrase and Maturation Inhibitors
  • Options if New Drugs Are Not Available
  • Options if New Drugs Are Not Available: Mega-HAART and Dual-Boosted PI Therapy
  • Options if New Drugs Are Not Available: Use a Nonsuppressive Holding Regimen
  • Options if New Drugs Are Not Available: Treatment Interruption
  • Summary and Conclusions
Disclaimer: The materials published on the Clinical Care Options Web site reflect the views of the reviewers or authors of the CCO material, not those of Clinical Care Options, LLC, the CME provider, or the companies providing educational grants. The materials may discuss uses and dosages for therapeutic products that have not been approved by the United States Food and Drug Administration. A qualified healthcare professional should be consulted before using any therapeutic product discussed. Readers should verify all information and data before treating patients or using any therapies described in these materials.

Jointly sponsored by Postgraduate Institute for Medicine and Clinical Care Options, LLC.

Contact Info

Educational grants provided by:

Educational grants support only the CME-certified components of this program.