Module

Debate: Are Noninvasive Tests Ready to Replace Liver Biopsy?

Source: Hepatitis Annual Update 2006

Debate: Are Noninvasive Tests Ready to Replace Liver Biopsy?

Program Director: Emmet B. Keeffe, MD, MACP

Faculty:

Nezam H. Afdhal, MD, FRCPI
Mitchell L. Shiffman, MD

CME CREDIT INFORMATION

Release Date: 06/30/06

Expiration Date: 06/29/07

Physicians: maximum of 1.5 AMA PRA Category 1 Credits™

Registered Nurses: 1.7 Nursing CE credits

Pharmacists: 1.4 contact hours (0.14 CEUs)

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Learning Objectives

Upon completion of this activity, participants should be able to:

Describe the role of liver biopsy and the noninvasive tests available (and in development) for the diagnosis of liver fibrosis and inflammation
Review the latest data supporting the use of liver biopsy or noninvasive tests, including data on risk, sensitivity, and specificity
Discuss the limitations of liver biopsy and noninvasive tests

Topics covered include:

In Favor of the Use of Noninvasive Tests
- Liver Biopsy
- Noninvasive Techniques
  - Radiology
  - Hepatic Elastography
  - Serum Markers of Fibrosis
    - Indirect Markers: Assessing Liver Function
    - Direct Markers: Assessing Fibrogenesis
- A Clinical Algorithm for Assessing Liver Fibrosis
In Favor of the Use of Liver Biopsy
- Indications for Liver Biopsy: Biopsy Diagnosis of Different Liver Diseases
- Biopsy to Assess Severity of Liver Disease and When to Initiate Therapy
- Biopsy to Assess Response to Therapy
- Noninvasive Markers to Assess Liver Disease

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