Learning Objectives
Upon completion of this activity, participants should be able to:
- Describe the available treatment options when initiating hepatitis B virus therapy
- Recount the factors involved in determining when to continue vs change current therapy
- List the endpoints of therapy used to determine when treatment should be discontinued
- Discuss new treatment data and the advantages and disadvantages of current treatment options
Topics covered include:
- What to Choose, When to Change and When to Stop
- What to Choose: Interferon Alfa
- What to Choose: Nucleos(t)ide Therapy
- De Novo Monotherapy vs Combination Therapy
- When to Change Therapy
- Predicting Resistance and Proactive HBV On-Treatment Management
- On-Treatment Roadmap Algorithm
- On-Treatment Management: Switch vs Add?
- When to Stop
- Summary: Implications for Clinical Practice